Signs and symptoms of Kawasaki disease

Physicians and researchers within the Division of Infectious Disease were able to diagnose and treat Andre's Kawasaki disease when others could not. Read more.

A child is diagnosed with "classic" or "typical" Kawasaki disease when he or she has a fever and at least four of the major symptoms (see below) in combination with changes in the laboratory blood tests such as an elevated sedimentation rate.

A diagnosis, however, can also be made if the child does not have all of the features noted above. This is referred to as "atypical" or "incomplete" Kawasaki disease.

Major symptoms

Fever and irritability often occur first in Kawasaki disease. The fever fluctuates from moderate (101-103° F) to high (104° F). The fever continues to rise and fall for as long as three weeks without treatment.

Rash usually develops early in the illness on the chest, back, diaper area and abdomen. In some cases, the rash may spread to the face, arms and legs. Often bright red in appearance, the rash ususally consists of poorly defined spots and blotches of various sizes.

Blood-shot eyes may develop, as well as a sensitivity to light. There is usually no drainage from the eyes.

The inside of the mout may become more red than ususal and the lips may become red, dry, swollen or cracked. The child's tongue may be coated, slightly swollen and red (described as "strawberry tongue").

Hands and feet may become red and are often swollen. Occasionally, swollen and painful joints (knees, hips, ankles or fingers) or a stiff neck will develop.

Lymph glands in the neck may become swollen, usually more on one side of the neck than the other. This is the least common of the major symptoms of Kawasaki disease.

Other complaints can include abdominal pain, vomiting, diarrhea, cough, listlessness and irritability.