Hypoplastic left heart syndrome

Image of heart

This drawing shows the abnormally small growth of the left ventricle found in patients with hypoplastic left heart syndrome.

Hypoplastic left heart syndrome (HLHS) is the abnormally small growth of the heart's major pumping chamber, the left ventricle. HLHS occurs in about one percent of all congenital heart disease. Essentially, the left ventricle is not functioning because the valves leading into and out of it are severely tight or not allowing any blood flow. Additionally, the main route out the left ventricle, the aorta, is also underdeveloped or nonfunctioning.

Symptoms of HLHS

The newborn baby may initially appear to be well during the first hours or even days of life. However, as the baby breathes on his own, the pressure in his lungs begins to decrease. The baby will appear to be sick, breathing quickly, not feeding, and showing a faster heart beat and congested lungs.

Image of heart This drawing shows the surgical repair of HLHS using the Norwood procedure.

Treatment for the condition

After a definitive diagnosis is formed, the baby will undergo the first surgery, called the Norwood procedure. The pulmonary artery is separated from the heart and connected to the small aorta. This enlarges the aorta and allows both oxygenated and deoxygenated blood to get to the body via the open pulmonary valve. Next a Gore-Tex tube is placed between the subclavian artery, the artery that runs under the collar bone, and the pulmonary artery to allow blood to flow from the baby's upper body directly to the lungs, bypassing the heart altogether. From the lungs, blood flows to the heart to be pumped out to the body, carrying oxygen.

When the child is five to eight months of age, the child will need to undergo a second surgery called the Glenn procedure. The Glenn procedure connects the superior vena cava to the pulmonary artery, after the Blalock-Taussig shunt is separated. This allows even more blood flow through the pulmonary arteries to the lungs. It also serves as a basis for the final surgery, the Fontan procedure.

The Fontan procedure takes the blood through the inferior vena cava directly to the pulmonary arteries with the superior vena cava blood. All the blood then goes to the lungs for oxygenation before going to the heart for pumping to the body.