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Treatment of Anxiety Disorders in Children and Adolescents

by Rebecca E. Ford, PhD

Summary

Despite the emergence of promising treatments, child anxiety is often under-identified and under-treated due to the lack of developmentally appropriate and reliable assessment at points of entry into the health care system. Child anxiety is often disregarded due to the misperception that anxiety in children is developmentally appropriate and that children will outgrow their fears. To complicate matters, anxiety in children presents differently from anxiety in adults and, therefore, may be overlooked or mislabeled. Childhood anxiety, however, has been linked to adolescent and adult anxiety, other psychological disorders, and substance abuse. Thus it is important for pediatricians to be familiar with developmentally appropriate anxiety, the unique presentation of anxiety in children, and ways to determine when further treatment is necessary. Increased awareness about evidence-based treatment for child anxiety would help pediatricians make informed referrals for mental health care.

Educational objectives

At the conclusion of this activity, participants will be able to:

  • Recognize developmentally appropriate anxiety in children and adolescents
  • Identify unique presentation of clinical anxiety in children and adolescents
  • Refer for appropriate treatment of pediatric anxiety

CME credit

This is an article from The Child's Doctor, Spring 2008 issue. You may take the quiz for learning purposes, but credits are no longer valid.

Author disclosures

Dr. Ford has no industry relationships to disclose and does not refer to products that are still investigational or not labeled for the use in discussion.


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Normal vs. abnormal anxiety

Anxiety is a natural emotion that can serve a protective function and heighten performance when present in mild to moderate levels. Anxiety becomes a problem when it causes persistent distress in the child's daily life or in family functioning. For example, when the child's functioning is impaired significantly in the areas of academic performance, peer and family relations, enjoyment of age-appropriate activities, and the will to live, the child should be referred for treatment with a mental health professional.

Familiarity with developmentally appropriate anxiety can help physicians determine whether a child's or adolescent's fears are out of the ordinary. Table 1 outlines the fears typically seen in children of various ages. As long as these fears are not disrupting developmentally appropriate activities, they would not meet criteria for an anxiety disorder.

 

Cultural and social concerns should also be considered when determining the clinical significance of anxiety symptoms. If the worries or fears are excessive and out of proportion relative to the situation, a referral for psychological follow-up should be considered. However, children with reality-based fears that have a minimal impact on functioning should not be diagnosed with an anxiety disorder. For example, if one encounters a child of Middle-Eastern descent who has concerns that he may be mistaken for a terrorist, the physician should be sensitive to the realities of discrimination and the life experience of this child living in the US at a time of US military engagement in the Middle East. Likewise, a common concern for urban youth is the safety of their parents traveling in a neighborhood overridden by gang violence. As long as these concerns are not causing a significant decline in the child's academic performance, social relationships, family interaction, or another area of functioning, these presentations would not warrant the diagnosis of an anxiety disorder.

Unique presentation of anxiety in children

In order to understand how anxiety presents in children, one must understand the role of avoidance in the development and sustenance of anxiety. Anxiety reactions include cognitive components (eg, catastrophic thoughts), physical components (eg, rapid heart beat, shortness of breath, nausea), emotional components (eg, fear, worry), and behavioral components (eg, avoidance and escape). The behavioral responses provide short-term relief from what the individual perceives as intolerable distress and/or disastrous outcomes. As long as the avoidance/escape response is practiced, the individual never has the opportunity to learn that the dreaded outcomes are unlikely or actually harmless. In other words, the avoidance of the feared stimuli serves to perpetuate the anxiety.

The desire to avoid or escape anxiety-evoking situations is quite intense and can result in extreme behaviors. Children often get increased attention from adults for externalizing problems, such as oppositional, inattentive, angry, aggressive, and disobedient behavior. This behavior is not well tolerated by teachers and parents and, therefore, more often receives intervention at an earlier point compared to internalizing symptoms. However, the fact that anxiety can masquerade in children as an externalizing disorder with many of the same symptoms often is overlooked. A child's temper tantrum and defiant behavior may be a manifestation of an overwhelming desire to avoid an anxiety-provoking situation at all costs. Inattention and forgetfulness can be attributed to the mental preoccupation and rumination common to many anxiety disorders. Furthermore, explosive and aggressive behavior may be explained by triggers (undetected by adults) that evoke re-experiencing symptoms (ie, flashbacks) in traumatized children.

Another consideration for detecting anxiety in young children is the level of verbal and cognitive development. Many children lack the verbal abilities and insight to be able to describe their internal state. Instead, anxiety may be manifested through somatic symptoms, including muscle aches, stomachaches/nausea, headaches, and sleep disturbance. Table 2 describes the most common anxiety disorders in children and the associated symptoms that might be presented in pediatric and primary care settings.

Adequate screening during primary care visits will assist in early detection and intervention. Whenever possible, data should be obtained from the child, parent, and teacher regarding the child's anxiety. Children may be more aware of internal distress than parents and teachers and may be able to shed light on the causes of externalizing problems (eg, attempts to avoid particular anxiety evoking situations). Use of self-report instruments for children age 8 years and over, such as the Multidimensional Anxiety Scale for Children (MASC)[1] or Screen for Child Anxiety Related Emotional Disorders (SCARED; available online)[2] can assist with screening and monitoring of treatment response for generalized, social, and separation anxiety, as well as panic symptoms and school refusal. The UCLA PTSD Index for DSM-IV (available free of charge with author's permission)[3] assesses post-traumatic symptoms in children 7 years of age and older.

Medication vs. psychotherapy

Options for evidence-based treatments for child anxiety include psychotherapy, psychopharmacological intervention, and a combination of these modalities. The referring physician should also be familiar with the current practice parameters for the treatment of childhood anxiety from the American Academy of Child and Adolescent Psychiatry4 in order to make informed recommendations to parents. These parameters indicate that the first line of treatment for mild to moderate anxiety should be psychotherapy. Moderate to severe anxiety may warrant combining medication and psychotherapy from the start because these children often have difficulty even attending therapy or discussing their fears without the help of medication. Medication is not considered a cure for a child's anxiety, but rather a tool to reduce severe anxiety symptoms and often to facilitate engagement in psychotherapy.

Cognitive-behavioral therapy

Cognitive-behavioral therapy (CBT) has emerged as the psychotherapeutic approach to child anxiety with the most empirical support. CBT typically involves psycho-education about anxiety, development of coping skills (relaxation, problem-solving, cognitive restructuring), and practice exercises involving gradual desensitization to anxiety-provoking stimuli/situations. It is a short-term, goal-oriented treatment that often is designed to be completed in 12–18 sessions. This therapy requires special training and has components particular to specific anxiety disorders. Many community mental health providers do not specialize in the delivery of CBT, but rather psychodynamic play therapy or interpersonal/supportive therapy. The challenge for the referring pediatrician is ensuring that one is referring to a psychotherapist trained in CBT. This can be facilitated by accessing the Association for Behavioral and Cognitive Therapies Web site (http://www.aabt.org) and searching for a therapist.

Specifically, the exposure module is considered the most potent ingredient of CBT. Exposure promotes the competing response to avoidance: facing one's fears in a controlled manner. At the beginning of treatment, the therapist works with the child and parent to construct a fear hierarchy. The child then exposes him/herself gradually to anxiety-evoking stimuli with the goal of habituation. Repeated exposures to feared situations afford the child in vivo learning experiences, which demonstrate that catastrophic consequences do not occur and that the child's anxiety is manageable. These exercises also need to be practiced often and for extended periods outside of therapy sessions in order to generalize treatment benefits.

Specific phobias, social anxiety, separation anxiety, and generalized anxiety: Exposure exercises for these common forms of anxiety break down frightening situations into manageable steps and allow the child to do them 1 at a time until mastery is achieved. Steps may include imaginal exposures, modeling by the therapist, tag-along procedures in which the child is accompanied through the process by the therapist, and, ultimately, increasingly independent attempts at facing fears.

Panic disorder: Interoceptive exposure is a technique used specifically to expose the child to the physical sensations common during panic attacks. During an exposure session, children perform exercises that will cause them to experience rapid heart rate, dizziness, and shortness of breath in a controlled setting so as to provide them with opportunities to experience that these symptoms do not necessarily precipitate a panic attack.

Obsessive-compulsive disorder (OCD): The exposure component for OCD also includes a response-prevention component. Not only is the child exposed imaginally and in vivo to frightening thoughts and situations, but s/he also is prevented from making the compulsive response that serves as an avoidance/escape strategy.

Post-traumatic stress disorder (PTSD): Trauma-focused cognitive behavioral therapy, likewise, includes an exposure component. In therapy, the child is asked to create a trauma narrative through discussion, writing, and art detailing the traumatic events with feelings and thoughts at the time of the events. Through repeated review of the trauma narrative, the child gradually becomes habituated to the once highly distressing narrative. After the trauma narrative is complete, cognitive restructuring (correction of illogical or false ideas about what happened) and meaning making can take place to help the child make sense of the event and to move forward in a healthy way.

CBT can be delivered in individual, family, and group formats. Treatment of PTSD is usually an individualized treatment. In general, there is an inverse relationship between parent involvement and age of the child in therapy (the younger the child, the more the parent is involved). Parents often serve as coaches for conducting exposure practice exercises at home. Group formats are particularly useful for children with social anxiety because the group itself will provide an exposure exercise for the attendees in addition to the other benefits, such as modeling, vicarious learning, constructive feedback, and peer support. CBT groups are also available for other types of anxiety disorders.

Conclusion

Anxiety disorders are some of the most frequently occurring psychological problems in children. Pediatricians who are informed and able to reliably identify clinical levels of anxiety in children, as well as the best treatment practices, are invaluable in guiding families to appropriate mental health professionals. Early intervention is essential in helping children manage their anxiety so it does not adversely impact their educational achievement, social lives, and family functioning during formative developmental stages.

REFERENCES

[1.] March JS, Parker JD, Sullivan K, et al. The Multidimensional Anxiety Scale for Children (MASC): Factor structure, reliability, and validity. J Am Acad Child Adolesc Psychiatry 1997;36:554-565.

[2.] Birmaher B, Brent DA, Chiappetta L, et al. Psychometric properties of the Screen for Child Anxiety Related Emotional Disorders Scale (SCARED): A replication study. J Am Acad Child Adolesc Psychiatry 1999;38:1230-1236.

[3.] Steinberg AM, Brymer MJ, Decker KB, Pynoos RS. The University of California at Los Angeles Post-Traumatic Stress Disorder Reaction Index. Current Psychiatry Reports 2004;6:96-100.

[4.] Connolly SD, Bernstein GA, et al. Practice parameter for the assessment and treatment of children and adolescents with anxiety disorders. Journal of the American Academy of Child and Adolescent Psychiatry 2007;46(2):267-283.


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Rebecca E. Ford, PhD
Staff psychologist, Child and Adolescent Psychiatry, Children's Memorial Hospital; Chicago, Illinois